Human Health And Disease MCQs With Answers – Part 1 (Class 12 Biology)
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Human Health and Disease MCQs with Answers – Part 1 (Class 12 Biology)

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11. Consider the following pathogen groups: I. Bacteria II. Viruses III. Fungi IV. Protozoans V. Helminths Which statement is biologically correct?
ⓐ. Only I and II can cause human disease
ⓑ. III and V are excluded because pathogens must be microscopic
ⓒ. I, II, III, IV and V can all include disease-causing organisms
ⓓ. Only organisms capable of independent cellular metabolism are pathogens
12. An organism lives in or on a host and obtains benefit while causing harm to that host. In the context of human disease, this relationship most directly describes
ⓐ. mutualism
ⓑ. independent nutrition
ⓒ. non-infectious degeneration
ⓓ. parasitism
13. An intestinal pathogen enters through contaminated food but must remain viable while passing through an acidic stomach environment before reaching a suitable site for multiplication. This situation best illustrates that successful pathogens require
ⓐ. complete independence from the host environment
ⓑ. elimination of all host digestive secretions before infection
ⓒ. transmission only through insect vectors
ⓓ. adaptation to conditions encountered within the host
14. After ingestion of contaminated food, Salmonella typhi establishes infection. Which sequence best represents the biological description of its early spread?
ⓐ. Bloodstream → skin → small intestine
ⓑ. Alveoli → bloodstream → large intestine
ⓒ. Small intestine → bloodstream → other organs
ⓓ. Lymphatic vessels → stomach → respiratory passages
15. A patient has sustained fever around \(39^\circ\text{C}\) to \(40^\circ\text{C}\), weakness, stomach pain, constipation, headache and loss of appetite. If the condition becomes severe, which complication is specifically associated with the suspected disease?
ⓐ. Fluid accumulation in alveoli
ⓑ. Severe intestinal perforation
ⓒ. Chronic lymphatic obstruction
ⓓ. Fungal invasion of nails
16. A food handler appears healthy but repeatedly contributes to transmission of typhoid, and laboratory evaluation of a symptomatic contact includes the associated diagnostic test. Which pairing is correct?
ⓐ. Carrier concept illustrated by Mary Mallon; ELISA used as the diagnostic test
ⓑ. Carrier concept illustrated by Mary Mallon; Widal test used as the diagnostic clue
ⓒ. Mechanical-vector concept illustrated by Mary Mallon; MRI used for diagnosis
ⓓ. Biological-vector concept illustrated by Mary Mallon; biopsy used for diagnosis
17. A bacterial infection primarily affects the alveoli of the lungs. The causative organisms are
ⓐ. S. typhi and Rhinovirus
ⓑ. E. histolytica and Ascaris
ⓒ. Microsporum and Trichophyton fungi
ⓓ. S. pneumoniae and H. influenzae
18. In severe pneumonia, respiratory difficulty develops primarily because
ⓐ. fluid-filled alveoli impair respiratory function
ⓑ. mucus disappears completely from the nasal passage
ⓒ. intestinal walls become perforated
ⓓ. lymphatic vessels of the lower limbs become chronically inflamed
19. Four exposure histories are recorded for a person living with someone who has pneumonia. I. Prolonged exposure to droplets released during coughing II. Sharing drinking glasses with the infected person III. Using utensils contaminated by the infected person's respiratory secretions IV. Inheriting a gene from the infected person's family Which combination contains plausible routes of pneumonia transmission?
ⓐ. I and IV only
ⓑ. II and III only
ⓒ. I, II and III
ⓓ. I, II, III and IV
20. A patient has nasal congestion, sore throat and cough, but examination does not indicate infection of the lungs. This localisation most strongly favours common cold because rhinoviruses mainly infect
ⓐ. the alveoli and pleural cavity
ⓑ. the small intestine and bloodstream
ⓒ. nose and respiratory passage, not lungs
ⓓ. the lymphatic vessels of the lower limbs
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